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PREDICTS Study

The Characterization and Prediction of Individual Functional Outcomes Trajectories in Schizophrenia Spectrum Disorders (PREDICTS) study aims to improve early identification and prediction of individual functional and recovery pathways for people living with schizophrenia spectrum disorders.

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Despite advances in the understanding and treatment of schizophrenia spectrum disorders (SSDs), people living with these mental health challenges often experience ongoing struggles with daily functioning, disability and low rates of personal recovery. The PREDICTS Study is focused on improving the early identification and prediction of how individuals living with an SSD will function and recover over time. This lays the groundwork for targeted interventions that will change the course of the illness and help promote functional recovery and overall well-being.

TAY Cohort Study

Following 3,000 youth over five years, the Toronto Adolescent and Youth (TAY) Cohort Study is uncovering who may be most at risk for developing psychosis.

Details

The TAY CAMH Cohort Study is a large-scale study of children and youth that aims to better understand who may be at risk of developing psychosis, so that we can provide more effective support. To do this, the study is following 3,000 youth between the ages of 11 and 24 over a five-year period, evaluating clinical outcomes, genetics, brain circuitry and key aspects of brain functioning, like memory and cognition. This data will be used to build a comprehensive picture of the whole individual, and map out the full mental health trajectories of treatment-seeking youth as they transition to adulthood. 

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TAY Cohort Study
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Investigating the mystery of youth psychosis
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The pieces of Alex
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HetNP Study

The Disentangling Heterogeneity Across Neuropsychiatric Disorders (HetNP) study leverages existing clinical and biological data collected from CAMH’s longitudinal cohort studies in order to help us identify new ways to treat mental health symptoms.

Details

The HetNP study builds bridges across CAMH's research fields by integrating longitudinal research data with pre-clinical and biological data in exciting new ways. Leveraging CAMH’s existing cohort studies, the project uses big data to deepen our understanding of the complex biological factors that contribute to symptom development. By integrating data from diverse research areas, the project seeks to discover new ways of looking at biomarkers (indicators in the body) which will ultimately enhance our understanding, diagnosis and treatment of mental illness.

Cognitive Dysfunction in the Addictions

The Cognitive Dysfunction in the Addictions research program is studying cognitive abilities in individuals seeking or receiving support for substance use, in order to better understand and support their recovery.

Details

The Cognitive Dysfunction in the Addictions research study aims to understand how cognitive difficulties with thinking, memory and attention (known as “executive dysfunction”) impact treatment outcomes, daily functioning and the quality of life of individuals with substance-use challenges. By integrating various research approaches and data collection methods (from brain imaging and bloodwork, to interviews and wearable technology), the study aims to understand the different factors contributing to cognitive dysfunction in individuals seeking or receiving support for their substance use, in order to better understand the nature of addiction and to support recovery.

CAMH Suicide Prevention Cohort Study

The CAMH Suicide Prevention Cohort Study is transforming suicide prevention research by examining the characteristics, trajectories, perspectives and outcomes of people experiencing suicidal ideation and behaviors.

Details

The CAMH Suicide Prevention Cohort Study aims to transform suicide prevention research and treatment by investigating the factors that may indicate a risk of suicidal ideation, and exploring the personal experiences and perspectives of those seeking care. Following 500 participants who visit the CAMH emergency department in a 12-month period, the study collects various data types (clinical, health services, qualitative, and biological) which will provide invaluable insight into the factors leading to suicidal behaviors and the subsequent clinical paths of those seeking care. These advancements in suicide prevention research will ultimately lead to suicide prevention interventions that meet patient needs, and have the potential to revolutionize the care and treatment of at risk individuals.

BrainHealth Databank

CAMH’s BrainHealth Databank is leveraging big data to identify new opportunities for detection, prevention and treatment of  mental illness, and is making personalized care possible.

Details

The BrainHealth Databank is a pioneering initiative focused on harnessing the power of big data to improve personalized mental health care and expedite clinical research, discovery and innovation. By combining data from a wide range of sources (including sleep and physical activity records from smartwatches, blood samples and brain images from labs, and assessments from health care visits) with advanced technologies such as algorithms, deep learning, and artificial intelligence, CAMH will be able to enhance its understanding of both individuals and larger populations. Through these data-driven discoveries, CAMH will be able to gain new insights into mental illness that will improve the lives of individuals living with mental health challenges.

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BrainHealth Databank
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Data-driven care is saving lives today
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Centre for Youth Bipolar Disorder

The Centre for Youth Bipolar Disorder’s mission is to improve outcomes for youth with bipolar disorder through cutting-edge treatment, research, education and advocacy.

Details

The Centre for Youth Bipolar Disorder (CYBD) is a leading clinical and research team dedicated to generating discoveries that will improve the detection, early intervention and treatment outcomes of youth with bipolar disorder. The CYBD makes use of a wide range of approaches, including brain imaging, genetics, exercise and novel psychotherapy, with a specific focus on investigating the connection between bipolar disorder and cardiovascular health. By examining the links between heart health and brain health, the CYBD aims to gain a better understanding of the causes and outcomes associated with youth bipolar disorder, which will ultimately lead to improved, holistic treatment strategies.

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Centre for Youth Bipolar Disorder
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